NANOBIOPHARMACEUTICS
Gold nanoparticle test
Today, the gradual flu tests are erroneous. The most accurate test is called PCR; however, it takes two weeks to get the results. When the gold nanoparticle test came along, the results could be found out immediately and cheaply. The test depends on the ability of the gold nanoparticles that disperse light in different ways. The nanoparticles are attached to the antibodies that tie specifically to the flu virus. Then, when the particles encircle the flu virus, the light is scattered around due to the transitions of the geometry. With the presence of the virus, the light will come out with a mesureably scattered pattern in the solution. The gold nanoparticle test is used for not only determining influenza but also any other kinds of diseases because the nanoparticles can be attached to any kinds of antibodies.
Drug Development
The Biopharmaceutics Classification System in Drug Development has been applied throughout drug discovery and development process. It is used to apply equivalence in brand and generic medicinal products, variation, fixed combinations, hybrids, and extensions. It categorizes drug substances into two sub-categorizes: slow vitro dissolution or rapid vitro solution. Then, it allocates the substances on aqueous solubility and intestinal permeabiblity of the active pharmaceutical ingredient. The Biopharmaceutics Classification System is used in different countries. In the United States, the BCS is used as a regulatory tool in the approval process of drugs. Although it is not directly used, in India, CDSCO's consideration of biowaiver is mostly on the topics that BCS covers. Also, in Japan, a guideline that is based on BCS is maintained. It is doubted that Japan will adopt BCS; however, it has been viewed positively in Japan's NIHS, which is Japan's National Institute of Health Sciences.
In the developed society today, it is possible to remove a tumor located in an accessible area. However, it was impossible to remove a tumor in an inaccessible area before a protocell weapon has been invented in New Mexico. Jeff Brinker and his team, Sandia National Labs, engineered a protocell capsule to deliver nanoparticles composed of toxins and RNA silencers to cancer cells. When it gets to the cancer cell, the protein of the protocell latches onto the tumor and encloses it. And then the nucleotides of the toxins get picked up by transport RNA and are brought to the nucleus, and destroys the tumor's DNA.